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Links……..For U

Staying Safe:

• 24 Hours at the Epicenter of the Coronavirus Pandemic: Doctors, nurses, a congressman, workers in deserted museums and theatres, men on early release from Rikers, and the newly unemployed strained to keep New York City, and themselves, going. (New Yorker)
• What if immunity to covid-19 doesn’t last? (MIT Technology Review)
• ‘Frostbite’ toes and other peculiar rashes may be signs of hidden coronavirus infection, especially in the young (Washington Post)
• We have to wake up: factory farms are breeding grounds for pandemics (The Guardian)

Aid and assistance:

• COVID Tests Are Free, Except When They’re Not (Kaiser Health News)
• Useful table of extended state tax filing deadlines  (Tax Foundation)
• Figuring Out Your Personal Finances Together (Wall Street Journal)

Staying Sane WFH:

• Signs You May Be Burning Out—and What to Do About It (Businessweek)
• “It Is Harrowing. It Is Daunting. It Is Overwhelming”: The Mental Toll of Coronavirus Is Crushing Medical Workers (Vanity Fair)
• Which epidemiologist do you believe? (UnHerd)
• Yuval Noah Harari: ‘Will coronavirus change our attitudes to death? Quite the opposite’ (The Guardian)

Vaccine & Treatment Updates:

• In Race for a Coronavirus Vaccine, an Oxford Group Leaps Ahead (New York Times)
• Some Countries Are Squashing the Coronavirus Curve. Vietnam Is One. (Wall Street Journal)
• Three potential coronavirus vaccines moving ahead in tests (Los Angeles Times)
• When will we get the Covid-19 vaccine? (UnHerdsee also How Long Will a Vaccine Really Take? (New York Times)
• UCSF team has discovered drugs that block coronavirus, paving way for ‘a better drug sooner’ (San Francisco Chronicle)
• The Secret Group of Scientists and Billionaires Pushing a Manhattan Project for Covid-19 (Wall Street Journal)

Resolving the Crisis:

• Dogs are being trained to sniff out coronavirus cases (Washington Post)
• Could contact tracing bring the US out of lockdown? (Vox)
• LA Becomes The First Major City In The US To Offer Free Testing To Every Resident, Even Those With No Symptoms (LAist)
• Why America’s coronavirus testing problem is still so difficult to solve (Vox)
• No Testing, No Treatment, No Herd Immunity, No Easy Way Out (The Atlantic)
• Poop may tell us when the coronavirus lockdown will end (LA Times)
• We Cannot “Reopen” America: The source of the economic shock is not government orders. It’s the pandemic. (The Bulwark)
• Reopening Plans Across U.S. Are Creating Confusing Patchwork (New York Times)

Post-Crisis

• What will cities look like once the lockdown lifts? (King’s College London)
• Five Ways the U.S. Military Will Change After the Pandemic (War on the Rocks)
• Will Travel Change After Coronavirus? Here’s What Experts Have to Say (Travel & Leisure)
• The Office You Left Is Not Going to Be the Office You Return To (Bloomberg)
• One Rich N.Y. Hospital Got Warren Buffett’s Help. This One Got Duct Tape. (New York Times)
• Covid-19’s future: small outbreaks, monster wave, or ongoing crisis (Stat)
• What the Coronavirus Crisis Reveals About American Medicine (New Yorker)
• The Immunity of the Tech Giants: When the pandemic is over, we most certainly should fear the industry more than ever (New York Times)

Venezuela asks Bank of England to sell its gold

Venezuela is asking the Bank of England to sell part of the South American nation’s gold reserves, send the proceeds to the United Nations to help with the country’s coronavirus-fighting efforts

Reuters with the report, citing “two sources with knowledge of the situation”.
  • It was not immediately evident how much gold Venezuela was asking the Bank of England to sell.
  • Venezuela’s information ministry and central bank did not respond to requests for comment.
  • The Bank of England said it does not comment on individual customer relationships.
Venezuela asks Bank of England to sell its gold

The number of potential coronavirus vaccines in development is now above 70

But, these are just two of many. The World Health Organization (WHO) says there are 70 coronavirus vaccines in development globally:
  • three are already already being tested in human trials
There are manufacturing contenders in the race:
  • Hong Kong-listed CanSino Biologics
  • Beijing Institute of Biotechnology
  • US’ Moderna and Inovio Pharmaceuticals
  • Pfizer and Sanofi also

Japan offers Avigan for free to countries fighting coronavirus

The flu drug Avigan will be made available at no cost to countries that ask for it to treat the novel coronavirus, the Japanese government announced Friday.

Chief Cabinet Secretary Yoshihide Suga told a news conference that about 30 countries have sought Avigan through diplomatic channels. “We are making arrangements to provide it for free,” he said.

Doing so will help expand clinical research into the drug, Suga said. At 2,617 cases as of Friday, Japan has relatively few of the more than 1 million infections worldwide, making broad clinical trials difficult.

Indonesia ordered 2 million doses of Avigan on March 20, and the country plans to begin clinical testing once the shipment arrives. The country has seen coronavirus cases there surge to 1,986, after going weeks without confirming infections in the early stages of the epidemic. Indonesia now has 181 deaths, placing it higher than South Korea, and second only to China in Asia.

Japan has also received a request from Turkey. Turkish Health Minister Fahrettin Koca met with Akio Miyajima, the Japanese ambassador to Ankara, last month and inquired about acquiring Avigan, diplomatic sources told the Nikkei Asian Review. (more…)

Trump drops idea of New York lockdown as U.S. death count crosses 2,000

President Donald Trump said on Saturday that he would issue a travel warning for the hard-hit New York area to limit the spread of the coronavirus, backing off from an earlier suggestion that he might try to cut off the region entirely.

“A quarantine will not be necessary,” he said on Twitter.

Trump’s announcement came as the U.S. death count crossed 2,100, more than double the level from two days ago. The United States has now recorded more than 122,000 cases of the respiratory virus, the most of any country in the world.

Since the virus first appeared in the United States in late January, Trump has vacillated between playing down the risks of infection and urging Americans to take steps to slow its spread.

Trump said on Saturday afternoon that he might impose a ban on travel in and out of New York and parts of New Jersey and Connecticut, the U.S. epicenter of the disease, to protect other states that have yet to bear the brunt. He offered few specifics.

Critics promptly called the idea unworkable, saying it would cause chaos in a region that serves as the economic engine of the eastern United States, accounting for 10 percent of the population and 12 percent of GDP. (more…)

US FDA grants orphan drug designation for potential Covid-19 treatment Remdesivir

This will hasten use of the drug to combat coronavirus

  • OOPD provides incentives for sponsors to develop products for rare diseases
  • program enables the development and marketing of drugs, biologics, and medical devices for rare diseases
  • Orphan Drug Designation Program provides orphan status to drugs and biologics which are defined as those intended for the safe and effective treatment, diagnosis or prevention of rare diseases/disorders that affect fewer than 200,000 people in the U.S., or that affect more than 200,000 persons but are not expected to recover the costs of developing and marketing a treatment drug.
Remdesivir is a nucleotide prodrug that blocks a key enzyme needed for viral replication

US House and Senate negotiators have reached agreement on emergency coronavirus bill

$8.3 billion to combat the coronavirus

The US House and Senate negotiators have reached an agreement on the emergency coronavirus bill. This according to House appropriations spokesman.

  • Total appropriations is for $8.3 billion to combat coronavirus
  • Bill to include 3 billion for research and development of vaccines, therapies and diagnostics
  • more than $300 million to help pay vaccine cause for those who cannot afford it
The House to vote on the funding today.
Meanwhile the IMF’ Kristalina Georgieva is out saying that the IMF has dedicated $50 billion to fund for virus help.
She adds:
  • expects growth this year will be below last year
  • central bank leaders and finance ministers are focused on what can do
  • great attention on liquidity to avoid credit crunch
  • nations are committed to coordinate on reaction to virus

China official PMIs February: Manufacturing 35.7 (expected 45.0) Non-manufacturing 29.6 (expected 51.0)

China’s economy was hit hard right from the Lunar New Year holiday and the weeks after from the coronavirus outbreak.

  • deaths now number >3,000 in China
  • Severe travel restrictions
  • Severe actions on public health
  • Business closures
Manufacturing 35.7, this is the lowest ever recorded for this indicator.
  • expected 45.0, prior 50.0
Non-manufacturing 29.6 … I mentioned during the week I was surprised the ‘expected’ for this was still in expansion. And here we are, deepest in contraction ever recorded
  • expected 51.0, prior 54.1
Composite 28.9
  • prior 53.0
China's economy coronavirus outbreak. 
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